All Supplements
5-HTP vs Vitex (Chasteberry)
Side-by-side comparison — benefits, dosage, forms, and research.
Feature
5-HTP
Vitex (Chasteberry)
Typical Dosage
50-100mg per day
400-500 mg daily of standardised extract (0.6% agnuside)
Best Form
Capsule
Standardised dry extract
Key Benefits
5
5
Evidence Rating
★★★
★★★
Best Time
Take with meals in divided doses, typically in the evening for sleep support
Morning with food; consistent daily use recommended for 2-3 menstrual cycles before assessing effectiveness
5-HTP Benefits
✓Mood support and depression relief
✓Improved sleep quality
✓Appetite suppression and weight management
✓Migraine prevention
✓Anxiety reduction
Vitex (Chasteberry) Benefits
✓Reduces premenstrual syndrome (PMS) symptoms including bloating and mood changes
✓Supports regular menstrual cycles and hormonal balance
✓May alleviate breast tenderness and cyclical mastalgia
✓Potentially improves fertility outcomes in women with luteal phase defects
✓Helps regulate progesterone levels in the luteal phase
Can You Take Both Together?
In most cases, 5-HTP and Vitex (Chasteberry) can be taken together safely. However, always check the interactions section of each supplement and consult a healthcare professional if you take medication.
Which Should You Choose?
Choose 5-HTP if your primary goal is: mood support and depression relief. Choose Vitex (Chasteberry) if your primary goal is: reduces premenstrual syndrome (pms) symptoms including bloating and mood changes. Many people take both as they target different aspects of health.
Disclaimer: This comparison is for educational purposes only. Always consult a healthcare professional before starting any supplement.