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Magnesium L-Threonate vs Glycine

Side-by-side comparison — benefits, dosage, forms, and research.

Magnesium L-Threonate

nootropics

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Glycine

amino acids

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Feature
Magnesium L-Threonate
Glycine
Typical Dosage
1,500-2,000mg (providing ~144mg elemental Mg)
3-5g daily
Best Form
Magnesium L-Threonate (Magtein)
Powder
Key Benefits
5
6
Evidence Rating
★★★
★★★★
Best Time
Evening — has calming/sleep-promoting effects
Evening for sleep benefits; anytime for general health

Magnesium L-Threonate Benefits

Crosses blood-brain barrier
May improve memory and learning
Sleep quality improvement
Brain magnesium levels
Potential neuroprotective effects

Glycine Benefits

Improves sleep quality and sleep onset
Supports collagen formation and joint health
Enhances cognitive function and memory
Reduces muscle wasting and supports muscle recovery
Promotes relaxation and reduces anxiety
Supports immune function

Can You Take Both Together?

In most cases, Magnesium L-Threonate and Glycine can be taken together safely. However, always check the interactions section of each supplement and consult a healthcare professional if you take medication.

Which Should You Choose?

Choose Magnesium L-Threonate if your primary goal is: crosses blood-brain barrier. Choose Glycine if your primary goal is: improves sleep quality and sleep onset. Many people take both as they target different aspects of health.

Disclaimer: This comparison is for educational purposes only. Always consult a healthcare professional before starting any supplement.