Magnesium L-Threonate
nootropics
A form of magnesium specifically developed to cross the blood-brain barrier. Researched for cognitive function, memory, and brain ageing.
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Benefits
Dosage
Typical Dose
1,500-2,000mg (providing ~144mg elemental Mg)
Upper Limit
2,000mg daily
Timing
Evening — has calming/sleep-promoting effects
Forms & Bioavailability
Magnesium L-Threonate (Magtein)
High brain bioavailability — patented form
Side Effects
Interactions
Research Summary
MIT-developed compound. One key RCT showed improved cognitive abilities in older adults. Limited but promising research. More studies needed to confirm benefits.
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The Bottom Line on Magnesium L-Threonate
Magnesium L-Threonate is moderately researched with promising but sometimes mixed evidence.It is most commonly used for crosses blood-brain barrier and may improve memory and learning. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Magnesium L-Threonate
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