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Best Supplements for Brain Health

The brain is the most metabolically active organ, consuming 20% of body energy. Long-term brain health requires neuroprotection, neuroplasticity support, adequate blood flow, and anti-inflammatory defence.

Top 5 Recommended Supplements

1

Lions Mane

1,500mg dual extract

Stimulates NGF and BDNF — the brain's growth factors for neurogenesis, myelination, and synaptic plasticity

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2

Omega-3 (DHA)

2-3g DHA-heavy

DHA comprises 30% of brain grey matter. Supports membrane fluidity, receptor signalling, and resolves neuroinflammation

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3

Phosphatidylserine

300mg

Major phospholipid in neuronal membranes. Supports memory, cognitive function, and cortisol regulation. Declines with age

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4

Creatine

5g

Brain energy buffer. 20% of body energy goes to the brain. Creatine improves cognition under stress and sleep deprivation

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5

Blueberry Extract / Anthocyanins

500mg

Cross the BBB, reduce neuroinflammation, enhance BDNF, and improve memory. The COSMOS trial showed significant cognitive benefits

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Sample Daily Stack

1

Morning: Lions Mane (1,500mg) + Omega-3 DHA (2g) + Creatine (5g) with breakfast

2

Afternoon: Phosphatidylserine (300mg) with lunch

3

Daily: Blueberry extract (500mg) or 1 cup fresh blueberries

Lifestyle Tips

Learn something new daily — cognitive challenge builds neural connections

Exercise is the strongest evidence-based brain protector (30 min daily)

Prioritise sleep — the glymphatic system clears brain waste during deep sleep

Socialise regularly — social isolation accelerates cognitive decline

Monitor cardiovascular health — what's good for the heart is good for the brain

Recommended

NAD

NAD Direct — 15% Off

The most innovative NAD+ delivery system. Smart Pens, patches, and supplements for cellular health and longevity.

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SG

Space Goods

Nootropic mushroom blends for focus, energy and calm.

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T

Tonic Health

Vitamin C, D3, Zinc and Elderberry in one daily drink. From 50p/day.

Get £15 off

This information is for educational purposes only and does not constitute medical advice. Supplement recommendations are based on published research but individual needs vary. Always consult a qualified healthcare professional before starting any supplement regimen. Amazon links are affiliate links.

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