Best Supplements for Migraine Prevention
Migraines involve cortical spreading depression, trigeminal nerve activation, and neuroinflammation. These supplements have strong evidence for reducing migraine frequency and severity.
Top 5 Recommended Supplements
Magnesium
400-600mgMigraine sufferers often have low brain magnesium. Supplementation reduces frequency by 41% in clinical trials
Buy on Amazon →Riboflavin (B2)
400mgImproves mitochondrial energy production in neurons. RCTs show 50% reduction in migraine frequency after 3 months
Buy on Amazon →CoQ10
300mgSupports neuronal mitochondrial function. Studies show 50% reduction in migraine days. Particularly effective in children/teens
Buy on Amazon →Feverfew
100-300mg (parthenolide standardised)Inhibits serotonin release and prostaglandin synthesis. Traditional migraine herb with clinical trial support
Buy on Amazon →Butterbur
75mg 2x daily (PA-free)Petadolex brand showed 48% reduction in migraine frequency. MUST be PA-free (pyrrolizidine alkaloids are hepatotoxic)
Buy on Amazon →Sample Daily Stack
Morning: Riboflavin (400mg) + CoQ10 (150mg) + Magnesium (200mg)
Afternoon: Feverfew (150mg) + CoQ10 (150mg)
Evening: Magnesium (400mg) + Butterbur (75mg PA-free)
Allow 3 months for full preventive effect to develop
Lifestyle Tips
Identify triggers: food diary tracking (common: aged cheese, wine, MSG, artificial sweeteners)
Maintain consistent sleep schedule — both too little and too much sleep trigger migraines
Stay hydrated — dehydration is a common trigger
Regular exercise reduces migraine frequency (but avoid sudden intense exercise)
Consider keeping a migraine diary to track frequency and identify patterns
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Try Huel →This information is for educational purposes only and does not constitute medical advice. Supplement recommendations are based on published research but individual needs vary. Always consult a qualified healthcare professional before starting any supplement regimen. Amazon links are affiliate links.