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Centrophenoxine

nootropics

Cholinergic compound that supports brain energy and lipofuscin clearance.

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Benefits

Increases brain acetylcholine levels
May clear lipofuscin (age pigment)
Supports brain energy metabolism
Potential anti-aging nootropic

Dosage

Typical Dose

250-500mg daily

Upper Limit

250-1000mg

Timing

Morning and early afternoon

Forms & Bioavailability

Capsule

Standard absorption

Side Effects

Nausea
Headache
Insomnia
Jaw clenching

Interactions

Anticholinergics
Cholinesterase inhibitors
Racetams (synergistic)

Research Summary

Developed in the 1960s as a cognitive enhancer. DMAE pro-drug with superior bioavailability. Studies show lipofuscin reduction in neurons and improved memory in elderly subjects.

The Bottom Line on Centrophenoxine

Centrophenoxine is moderately researched with promising but sometimes mixed evidence.It is most commonly used for increases brain acetylcholine levels and may clear lipofuscin (age pigment). As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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