Pregnenolone
hormonal support
Master precursor hormone from which all steroid hormones are synthesised.
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Benefits
Dosage
Typical Dose
10-30mg daily
Upper Limit
5-50mg
Timing
Morning
Forms & Bioavailability
Capsule
Standard absorption
Sublingual
Standard absorption
Cream
Standard absorption
Side Effects
Interactions
Research Summary
Declines significantly with age. Small studies show cognitive and mood benefits in older adults. As a precursor hormone, effects vary based on individual downstream conversion pathways.
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The Bottom Line on Pregnenolone
Pregnenolone is moderately researched with promising but sometimes mixed evidence.It is most commonly used for precursor to all steroid hormones and may support memory and cognitive function. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Pregnenolone
See how Pregnenolone can help with specific health goals: