Serrapeptase 120000 SPU

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Serrapeptase is a proteolytic enzyme derived from silkworm intestines that breaks down non-living tissue and proteins. It is traditionally used in Asia for inflammation reduction and may support respiratory and circulatory health.

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Benefits

✓Reduces inflammation and swelling

✓May improve respiratory clearance

✓Supports tissue repair and recovery

✓Potential cardiovascular support

✓May reduce scar tissue formation

Dosage

Typical Dose

120000 SPU once or twice daily

Upper Limit

240000 SPU daily in divided doses

Timing

On an empty stomach, 2 hours before or after meals for optimal absorption

Forms & Bioavailability

Enteric-coated tablets

Highest bioavailability; coating protects enzyme from stomach acid

Capsules

Variable depending on enteric coating quality

Side Effects

⚠Mild nausea or gastrointestinal upset

⚠Rare allergic reactions in silkworm-sensitive individuals

⚠Possible blood thinning effects at high doses

Interactions

⚡Blood thinners (warfarin, aspirin) may have additive effects

⚡Antiplatelet medications may increase bleeding risk

⚡May interact with other proteolytic enzymes

Research Summary

Evidence for serrapeptase remains limited with most studies conducted in Asia. Some research suggests benefit for inflammation and post-surgical oedema, though rigorous clinical trials in Western populations are lacking. Further investigation is needed to establish optimal dosing and efficacy.

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The Bottom Line on Serrapeptase 120000 SPU

Serrapeptase 120000 SPU is moderately researched with promising but sometimes mixed evidence.It is most commonly used for reduces inflammation and swelling and may improve respiratory clearance. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.