Yohimbine HCl
herbs
Yohimbine HCl is an alkaloid derived from the bark of the Pausinystalia yohimbe tree, functioning as an alpha-2 adrenergic receptor antagonist. It is commonly used to support fat loss, athletic performance, and sexual function through increased adrenaline and noradrenaline signalling.
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Benefits
Dosage
Typical Dose
5-20 mg per day
Upper Limit
20-30 mg per day
Timing
On an empty stomach in the morning or pre-workout; split into 2-3 doses
Forms & Bioavailability
Yohimbine HCl Powder
High bioavailability; rapidly absorbed on empty stomach
Yohimbine HCl Capsules
High bioavailability; consistent dosing with slower absorption than powder
Side Effects
Interactions
Research Summary
Clinical evidence supports yohimbine's role in modest fat loss promotion and sexual function improvement, particularly in men with erectile dysfunction. However, effects are inconsistent and modest, with considerable individual variability. Safety concerns regarding cardiovascular stress and anxiety warrant cautious use and medical consultation, especially for those with hypertension or heart conditions.
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The Bottom Line on Yohimbine HCl
Yohimbine HCl is moderately researched with promising but sometimes mixed evidence.It is most commonly used for may support fat loss and weight management and potential improvement in exercise performance. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Yohimbine HCl
See how Yohimbine HCl can help with specific health goals: