Alpha GPC
NootropicsKey Benefits
How It Works
Alpha-glycerophosphocholine crosses the blood-brain barrier efficiently, releasing choline for acetylcholine synthesis and glycerophosphate for phospholipid membrane repair. It's the most efficient choline source for brain levels. Also stimulates growth hormone release acutely.
Dosage & Timing
Recommended Dosage
300-600 mg daily (up to 1,200 mg)
Best Time to Take
Morning or pre-workout for cognitive enhancement
Recommended Form
Alpha GPC 50% (standard potency) capsules
Side Effects
Generally well-tolerated. Headaches, dizziness, GI discomfort rarely. Very high chronic doses may have cardiovascular concerns.
Drug Interactions
May enhance effects of anticholinergic and cholinergic drugs. Consider stroke risk at very high chronic doses (recent research).
What Does The Research Say?
Studies show cognitive benefits in Alzheimer's (1,200mg/day), enhanced power output in athletes, and increased growth hormone. The most efficient way to raise brain acetylcholine. Recent observational study raised stroke concerns at high chronic doses.
Where to Buy
Buy Alpha GPC on Amazon
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This information is for educational purposes only and does not constitute medical advice. Researched by The NexoraOS Team, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.