Citrulline
Sports PerformanceKey Benefits
How It Works
L-Citrulline is converted to arginine in the kidneys more effectively than direct arginine supplementation. Arginine is then converted to nitric oxide (NO) by eNOS, vasodilating blood vessels. This improves blood flow, nutrient delivery, and waste product removal from muscles.
Dosage & Timing
Recommended Dosage
6-8 g L-citrulline or 8-10 g citrulline malate daily
Best Time to Take
30-60 minutes pre-workout
Recommended Form
L-Citrulline (pure) or Citrulline Malate 2:1
Side Effects
Very well-tolerated. Rare GI discomfort. May lower blood pressure.
Drug Interactions
May enhance effects of blood pressure medications, PDE5 inhibitors, and nitrates. Caution with low blood pressure.
What Does The Research Say?
Research shows improved exercise performance, reduced soreness, and enhanced blood flow. Superior to arginine supplementation for raising arginine levels (paradoxically). Citrulline malate adds malic acid for additional Krebs cycle support.
Where to Buy
Buy Citrulline on Amazon
Compare prices and read reviews →
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Try Huel →This information is for educational purposes only and does not constitute medical advice. Researched by the editorial team at NexoraOS, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.