Conjugated Linoleic Acid
FatsKey Benefits
How It Works
CLA (primarily the t10,c12 isomer) inhibits lipoprotein lipase (reducing fat storage), activates PPAR-alpha (increasing fat oxidation), and enhances apoptosis in adipocytes. The c9,t11 isomer has anti-inflammatory and immune-modulating properties.
Dosage & Timing
Recommended Dosage
3,000-6,000 mg daily
Best Time to Take
With meals, split into 3 doses
Recommended Form
Tonalin or Clarinol CLA (80% active isomers)
Side Effects
GI discomfort, may worsen insulin sensitivity in some. May increase liver fat markers. Choose quality products.
Drug Interactions
May interact with blood thinners and diabetes medications.
What Does The Research Say?
Meta-analyses show modest but consistent fat loss (0.05 kg/week). Effects are small but real. Concerns about insulin sensitivity and liver effects in some studies. Most beneficial for body recomposition alongside resistance training.
Where to Buy
Buy Conjugated Linoleic Acid on Amazon
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Try Huel →This information is for educational purposes only and does not constitute medical advice. Researched by the editorial team at NexoraOS, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.