DHEA
HormonesKey Benefits
How It Works
Dehydroepiandrosterone is the most abundant steroid hormone, serving as a precursor to androgens and oestrogens. Levels peak at 25 and decline ~2% per year. It also has direct receptor activity (sigma-1, GABA-A modulation) and supports immune function.
Dosage & Timing
Recommended Dosage
25-50 mg daily (test levels first)
Best Time to Take
Morning to mimic natural production pattern
Recommended Form
Micronised DHEA capsules (pharmaceutical grade)
Side Effects
Acne, hair growth, hormonal imbalance if dose too high. Women need lower doses. May cause mood changes. TEST LEVELS before supplementing.
Drug Interactions
CRITICAL: May interact with hormone therapies, aromatase inhibitors, and liver-metabolised drugs. Avoid with hormone-sensitive cancers.
What Does The Research Say?
Research shows benefits for adrenal insufficiency and aging-related decline. May improve bone density and body composition in elderly. MUST test DHEA-S levels before supplementing. Prescription in UK, OTC in US.
Where to Buy
Buy DHEA on Amazon
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Try Huel →This information is for educational purposes only and does not constitute medical advice. Researched by the editorial team at NexoraOS, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.