GABA
Amino AcidsKey Benefits
How It Works
Gamma-aminobutyric acid is the brain's main inhibitory neurotransmitter. Supplemental GABA's ability to cross the blood-brain barrier is debated, but it may act via the enteric nervous system (gut-brain axis) and peripheral GABA receptors. Also shown to increase growth hormone transiently.
Dosage & Timing
Recommended Dosage
250-750 mg daily
Best Time to Take
Evening before bed, or as needed for anxiety
Recommended Form
PharmaGABA (natural fermented form)
Side Effects
Generally safe. Drowsiness, tingling, shortness of breath at high doses rarely. May feel unusual at first.
Drug Interactions
May enhance effects of sedatives, benzodiazepines, and anti-anxiety medications. Start low.
What Does The Research Say?
Blood-brain barrier penetration is controversial, yet human studies show measurable relaxation effects (possibly gut-mediated). PharmaGABA (natural form) shows better results than synthetic GABA in studies.
Where to Buy
Buy GABA on Amazon
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