Glycine
Amino AcidsKey Benefits
How It Works
Glycine acts as an inhibitory neurotransmitter via glycine receptors, lowering core body temperature (promoting sleep onset), protecting neurons from excitotoxicity, and serving as a building block for collagen, glutathione, creatine, and haem. The brain uses it as both excitatory (NMDA co-agonist) and inhibitory.
Dosage & Timing
Recommended Dosage
3-5 g daily for sleep (up to 10g for collagen support)
Best Time to Take
3g before bed for sleep. With vitamin C for collagen support.
Recommended Form
Pure glycine powder (sweet taste, easily mixed)
Side Effects
Very safe. Sweet taste. Extremely rare side effects. May cause mild nausea at very high doses.
Drug Interactions
May enhance effects of clozapine. Generally very safe with medications.
What Does The Research Say?
Research shows 3g before bed improves sleep quality, reduces daytime sleepiness, and improves cognitive function the next day. Essential for glutathione synthesis alongside NAC and glutamate. Most people are glycine-deficient for optimal collagen production.
Where to Buy
Buy Glycine on Amazon
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