Inositol
VitaminsKey Benefits
How It Works
Myo-inositol is a secondary messenger in insulin signalling, serotonin receptor function, and calcium mobilisation. It's the precursor to phosphatidylinositol in cell membranes. In the brain, it modulates serotonin and GABA receptor sensitivity, explaining its anxiolytic effects.
Dosage & Timing
Recommended Dosage
2,000-4,000 mg for PCOS/anxiety (up to 18g for OCD)
Best Time to Take
Before bed for sleep, or split doses for PCOS/anxiety
Recommended Form
Myo-inositol powder (or 40:1 myo/D-chiro blend for PCOS)
Side Effects
Very well-tolerated even at high doses. GI discomfort at very high doses (>12g). Mild drowsiness.
Drug Interactions
May enhance effects of SSRIs (can be beneficial). May affect lithium levels.
What Does The Research Say?
Strong evidence for PCOS (insulin sensitisation, ovulation restoration) at 4g/day. Research supports anxiety, OCD (12-18g), and sleep. The 40:1 ratio of myo-inositol to D-chiro-inositol mirrors natural plasma levels.
Where to Buy
Buy Inositol on Amazon
Compare prices and read reviews →
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Try Huel →This information is for educational purposes only and does not constitute medical advice. Researched by the editorial team at NexoraOS, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.