Milk Thistle
Liver SupportKey Benefits
How It Works
Silymarin (the active complex from milk thistle) protects hepatocytes by stabilising cell membranes, increasing glutathione by 35%, stimulating ribosomal RNA polymerase (liver cell regeneration), and inhibiting NF-kB inflammation pathways. Silybin is the most potent component.
Dosage & Timing
Recommended Dosage
200-400 mg silymarin (standardised 80%) daily
Best Time to Take
With meals, split into 2-3 doses
Recommended Form
Silymarin phytosome (Siliphos) for best absorption
Side Effects
Very well-tolerated. Mild GI discomfort or laxative effect rarely. Allergic reactions in ragweed-sensitive individuals.
Drug Interactions
May affect CYP enzymes altering drug metabolism. Discuss with doctor if on medications processed by the liver.
What Does The Research Say?
Well-established hepatoprotective effects in research. Used clinically in Europe for liver disease. Studies show benefit for fatty liver disease, hepatitis, and cirrhosis as adjunct therapy. Phytosome form improves bioavailability.
Where to Buy
Buy Milk Thistle on Amazon
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This information is for educational purposes only and does not constitute medical advice. Researched by The NexoraOS Team, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.