NR (Nicotinamide Riboside)
LongevityKey Benefits
How It Works
Nicotinamide riboside enters cells via ENT transporters and is phosphorylated by NR kinases to NMN, then converted to NAD+. This pathway is distinct from NMN's route. NR has the most human clinical trial data of any NAD+ precursor.
Dosage & Timing
Recommended Dosage
300-1,000 mg daily
Best Time to Take
Morning with or without food
Recommended Form
Niagen (TRU NIAGEN) branded form
Side Effects
Well-tolerated in clinical trials up to 2,000 mg/day. Mild nausea, fatigue, headaches reported occasionally.
Drug Interactions
Similar theoretical concerns as NMN regarding cancer. No established drug interactions in clinical trials.
What Does The Research Say?
ChromaDex's Niagen (NR) has the most rigorous human trial data. Proven to raise NAD+ levels dose-dependently. The NASDAQ-listed company has funded extensive research. Debate continues on NR vs NMN efficacy.
Where to Buy
Buy NR (Nicotinamide Riboside) on Amazon
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