Resveratrol
LongevityKey Benefits
How It Works
Resveratrol activates SIRT1 (a sirtuin deacetylase linked to longevity), AMPK (cellular energy sensor), and Nrf2 (antioxidant response). It mimics some effects of caloric restriction. Also inhibits NF-kB (inflammation) and modulates oestrogen receptors.
Dosage & Timing
Recommended Dosage
150-500 mg trans-resveratrol daily
Best Time to Take
Morning with a fat-containing meal. Some take with NMN for synergy.
Recommended Form
Trans-resveratrol, micronised or liposomal form
Side Effects
GI discomfort at high doses. Oestrogenic activity may be a concern for hormone-sensitive conditions. May thin blood.
Drug Interactions
May interact with blood thinners, CYP450 substrates, and hormone therapies. Discuss with doctor if on medications.
What Does The Research Say?
Animal studies show remarkable longevity benefits, but human translation is debated. The French Paradox hypothesis. Recent focus on synergy with NAD+ precursors. Bioavailability is a major challenge addressed by newer formulations.
Where to Buy
Buy Resveratrol on Amazon
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This information is for educational purposes only and does not constitute medical advice. Researched by The NexoraOS Team, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.