Riboflavin
VitaminsKey Benefits
How It Works
Vitamin B2 is the precursor to FAD and FMN, cofactors for over 100 enzymes (flavoproteins) including those in the electron transport chain, fatty acid oxidation, and the glutathione reductase antioxidant system. Essential for methylation cycle support via MTHFR enzyme.
Dosage & Timing
Recommended Dosage
25-400 mg daily (400mg for migraine prevention)
Best Time to Take
With food for better absorption. Split doses for higher amounts.
Recommended Form
Riboflavin or riboflavin-5-phosphate (active form)
Side Effects
Very safe. Causes bright yellow urine (harmless). Rare diarrhoea at very high doses.
Drug Interactions
May be depleted by oral contraceptives, TCAs, and some antibiotics.
What Does The Research Say?
Strong evidence for migraine prevention at 400mg daily (multiple RCTs). Essential for MTHFR function (supports methylation). Deficiency common in elderly and those on restricted diets.
Where to Buy
Buy Riboflavin on Amazon
Compare prices and read reviews →
Pair Supplements With Smart Training
RYVVA tracks your workouts, nutrition, and recovery — so your supplements fuel real progress.
Try RYVVA Free →Testosterone Support From Voy
UK-based TRT and hormone optimisation. Clinician-led, delivered to your door. Blood tests, prescriptions, and ongoing monitoring.
Learn More at Voy →Try Space Goods
Nootropic mushroom blends for focus, energy, and calm. Lion\'s Mane, Cordyceps, Ashwagandha in one daily drink.
Shop Space Goods →LA Muscle Supplements
Premium sports nutrition — protein, pre-workout, testosterone boosters, and fat burners. UK-made.
Shop LA Muscle →Healthy Meals Delivered
Chef-prepared, macro-balanced meals delivered to your door. Perfect for hitting your nutrition goals.
Try Simmer Eats →Horace — Men's Skincare
Premium French skincare for men. Natural ingredients, no fuss. Cleansers, moisturisers, and grooming essentials.
Shop Horace →Vitality Health Insurance
Rewards you for being healthy. Gym discounts, Apple Watch deals, and wellness perks with your health cover.
Get a Vitality quote →Huel — Complete Nutrition
Nutritionally complete meals, shakes, and bars. 26 vitamins and minerals in every serving.
Try Huel →This information is for educational purposes only and does not constitute medical advice. Researched by the editorial team at NexoraOS, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.