Thiamine
VitaminsKey Benefits
How It Works
Vitamin B1 is a cofactor for pyruvate dehydrogenase (links glycolysis to Krebs cycle), alpha-ketoglutarate dehydrogenase (Krebs cycle), transketolase (pentose phosphate pathway), and branched-chain alpha-keto acid dehydrogenase. Essential for energy production from carbohydrates.
Dosage & Timing
Recommended Dosage
50-300 mg daily (benfotiamine for neuropathy)
Best Time to Take
With meals, morning preferred
Recommended Form
Benfotiamine (fat-soluble) or thiamine HCl
Side Effects
Very safe even at high doses (water-soluble, excess excreted). Rare allergic reactions with injection.
Drug Interactions
May be depleted by alcohol, diuretics, and metformin. Enhances glucose metabolism.
What Does The Research Say?
Critical for preventing Wernicke's encephalopathy (especially in alcohol use). Research on benfotiamine (fat-soluble form) shows benefits for diabetic neuropathy and AGE reduction. Often depleted in metabolically stressed individuals.
Where to Buy
Buy Thiamine on Amazon
Compare prices and read reviews →
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Try Huel →This information is for educational purposes only and does not constitute medical advice. Researched by the editorial team at NexoraOS, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.