Vitamin B6
VitaminsKey Benefits
How It Works
Pyridoxal-5-phosphate (P5P) is a cofactor for over 150 enzymes, primarily in amino acid metabolism. Essential for neurotransmitter synthesis (serotonin, dopamine, GABA, norepinephrine), haemoglobin formation, homocysteine to cysteine conversion, and immune cell production.
Dosage & Timing
Recommended Dosage
25-100 mg P5P daily (do not exceed 200 mg long-term)
Best Time to Take
With meals, morning or afternoon preferred
Recommended Form
Pyridoxal-5-Phosphate (P5P active form)
Side Effects
Peripheral neuropathy at chronic high doses (>200mg/day). Tingling, numbness. Photosensitivity. Use P5P form for safety.
Drug Interactions
May reduce effectiveness of levodopa and phenytoin. Depleted by oral contraceptives, isoniazid, and penicillamine.
What Does The Research Say?
P5P form is preferred (bypasses liver conversion). Commonly deficient in women on oral contraceptives. Research supports mood benefits via neurotransmitter synthesis. Essential for proper GABA function.
Where to Buy
Buy Vitamin B6 on Amazon
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This information is for educational purposes only and does not constitute medical advice. Researched by The NexoraOS Team, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.