Vitamin K2
VitaminsKey Benefits
How It Works
Vitamin K2 (menaquinone) activates matrix Gla protein (MGP) and osteocalcin through carboxylation. MGP inhibits calcium deposition in arteries while osteocalcin directs calcium into bone matrix. This dual action makes K2 essential for proper calcium distribution.
Dosage & Timing
Recommended Dosage
100-200 mcg MK-7 daily
Best Time to Take
With a fat-containing meal, morning or evening
Recommended Form
MK-7 (from natto) for daily use, MK-4 for bone-specific
Side Effects
Very safe. No known toxicity at supplemental doses. Does not promote blood clotting beyond normal levels.
Drug Interactions
CRITICAL: Interacts with warfarin and other blood thinners. Consult doctor if on anticoagulants.
What Does The Research Say?
The Rotterdam Study showed K2 intake associated with reduced cardiovascular mortality. Japanese research on MK-4 shows bone density benefits. MK-7 has longer half-life and better bioavailability than MK-4.
Where to Buy
Buy Vitamin K2 on Amazon
Compare prices and read reviews →
Recommended
Affiliate links — we may earn a commission at no extra cost to you.
This information is for educational purposes only and does not constitute medical advice. Researched by The NexoraOS Team, supplement user since 2018. Always consult a qualified healthcare professional before starting any supplement. Individual results may vary. Amazon links are affiliate links.