Andrographis paniculata
herbs
Andrographis paniculata, commonly known as King of Bitters, is a traditional Ayurvedic and Chinese herbal remedy known for its bitter compounds, particularly andrographolides. It has been used historically for immune support and respiratory health, with emerging scientific interest in its potential immunomodulatory and anti-inflammatory properties.
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Benefits
Dosage
Typical Dose
300-400 mg daily of standardised extract (containing 4-6% andrographolides)
Upper Limit
1000-1200 mg daily in divided doses
Timing
With meals to enhance absorption and reduce gastrointestinal irritation
Forms & Bioavailability
Standardised dry extract powder
Moderate (4-6% andrographolides)
Capsules (standardised extract)
Moderate to good
Liquid tincture
Variable (depends on extraction method)
Whole dried herb decoction
Lower (non-standardised)
Side Effects
Interactions
Research Summary
Evidence is moderately promising but mixed. Several randomised controlled trials suggest benefit for reducing duration of upper respiratory infections and symptoms. The andrographolide compounds show immunomodulatory activity in vitro and in animal studies. However, human trials are often small and of variable quality. More rigorous long-term safety and efficacy data are needed. Traditional use in Ayurveda and Traditional Chinese Medicine extends back centuries, though scientific validation remains incomplete.
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The Bottom Line on Andrographis paniculata
Andrographis paniculata is moderately researched with promising but sometimes mixed evidence.It is most commonly used for immune system support and enhanced immune response and anti-inflammatory effects on respiratory and gastrointestinal tissues. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Andrographis paniculata
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