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Andrographis Paniculata

herbs

Andrographis paniculata, commonly known as King of Bitters, is a traditional Ayurvedic herb native to South Asia with potent immunomodulatory and anti-inflammatory properties. It contains bioactive compounds called andrographolides that support immune function and may reduce the severity and duration of upper respiratory infections.

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Benefits

Supports immune system function
Reduces inflammation
May shorten cold and flu duration
Antioxidant support
Supports respiratory health
Traditional digestive aid

Dosage

Typical Dose

400-500mg daily

Upper Limit

1000-1500mg daily

Timing

With meals to minimise gastrointestinal upset

Forms & Bioavailability

Standardised extract (andrographolides 10-30%)

Highest bioavailability; most commonly used in clinical research

Whole herb powder

Lower standardisation; variable potency

Capsules

Convenient form; efficacy depends on extract standardisation

Side Effects

Bitter taste
Gastrointestinal upset or nausea
Appetite suppression
Rash or allergic reactions (rare)
Headache

Interactions

May potentiate anticoagulants and antiplatelet drugs
Possible interaction with immunosuppressant medications
May reduce blood sugar; caution with diabetes medications

Research Summary

Multiple clinical trials demonstrate andrographis efficacy in reducing upper respiratory infection symptoms and duration, particularly when taken prophylactically. Research supports its traditional use for immune support, though more studies are needed to establish optimal dosing protocols and long-term safety. The herb shows promise as an adjunctive therapy but should not replace conventional medical treatment for serious infections.

The Bottom Line on Andrographis Paniculata

Andrographis Paniculata is well-researched with strong evidence supporting its primary benefits.It is most commonly used for supports immune system function and reduces inflammation. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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