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Arachidonic Acid

performance

Omega-6 fatty acid that amplifies the inflammatory signalling needed for muscle growth.

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Benefits

Amplifies exercise-induced muscle signalling
May increase lean body mass
Supports strength gains
Enhances training-induced inflammation for adaptation

Dosage

Typical Dose

1500mg daily

Upper Limit

750-2000mg

Timing

Pre-workout or with meals

Forms & Bioavailability

Softgel

Standard absorption

Capsule

Standard absorption

Side Effects

Joint aches
Headache
May worsen inflammatory conditions

Interactions

NSAIDs (opposing mechanism)
Blood thinners
Omega-3 supplements (may counteract)

Research Summary

University of Tampa RCT showed increased lean mass, strength, and anaerobic power vs. placebo. Works by amplifying prostaglandin response to exercise. Not suitable for those with inflammatory conditions.

The Bottom Line on Arachidonic Acid

Arachidonic Acid is moderately researched with promising but sometimes mixed evidence.It is most commonly used for amplifies exercise-induced muscle signalling and may increase lean body mass. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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