Ashwagandha KSM-66
adaptogens
KSM-66 is a clinically-studied ashwagandha extract standardised to 5% withanolides, the bioactive compounds responsible for its adaptogenic properties. This full-spectrum extract maintains the plant's natural ratio of alkaloids and has demonstrated efficacy in reducing stress, anxiety, and cortisol levels whilst supporting mental clarity and resilience.
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Benefits
Dosage
Typical Dose
300-600mg daily
Upper Limit
1200mg daily
Timing
With meals; divided doses optimal for stress management
Forms & Bioavailability
Capsule
High; standardised extract ensures consistent withanolide content
Powder
High; full-spectrum retention with flexible dosing
Tablet
High; convenient standardised dosing
Side Effects
Interactions
Research Summary
KSM-66 has undergone multiple clinical trials demonstrating significant reductions in anxiety and stress markers compared to placebo. Studies support its efficacy for cortisol management, sleep improvement, and cognitive performance in both acute and chronic stress contexts. The standardised extract format ensures reproducible results across research applications.
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The Bottom Line on Ashwagandha KSM-66
Ashwagandha KSM-66 is well-researched with strong evidence supporting its primary benefits.It is most commonly used for stress and anxiety reduction and cortisol regulation. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Ashwagandha KSM-66
See how Ashwagandha KSM-66 can help with specific health goals: