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Bromelain

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Bromelain is a proteolytic enzyme derived from pineapple stems that aids protein digestion and reduces inflammation. It has been traditionally used to support digestive health, wound healing, and post-surgical recovery. Evidence suggests moderate efficacy for specific applications, though results are mixed across studies.

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Benefits

Supports protein digestion and nutrient absorption
May reduce inflammation and swelling
Promotes faster wound and tissue healing
Could improve joint mobility and flexibility
May support recovery from minor injuries or surgery

Dosage

Typical Dose

500-1000 mg daily

Upper Limit

2000 mg daily

Timing

Between meals on an empty stomach for systemic effects; with meals for digestive support

Forms & Bioavailability

Capsules

Moderate (35-60% absorption)

Tablets

Moderate (35-60% absorption)

Powder

Good (40-70% absorption)

Fresh pineapple

Variable (enzyme degraded by stomach acid)

Side Effects

Mouth irritation or soreness when chewed or held in mouth
Gastrointestinal upset, nausea, or diarrhoea in sensitive individuals
Allergic reactions including rash or swelling in susceptible persons

Interactions

May potentiate anticoagulants and antiplatelet medications, increasing bleeding risk
Could interact with ACE inhibitors and blood pressure medications
May enhance antibiotic absorption and effectiveness

Research Summary

Clinical evidence for bromelain is moderately supportive but inconsistent. Multiple studies indicate potential benefits for post-surgical oedema reduction and joint inflammation, though quality and sample sizes vary considerably. More rigorous, large-scale trials are needed to establish optimal dosing and confirm efficacy for specific conditions.

The Bottom Line on Bromelain

Bromelain is moderately researched with promising but sometimes mixed evidence.It is most commonly used for supports protein digestion and nutrient absorption and may reduce inflammation and swelling. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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