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Centella Asiatica

herbs

Centella asiatica, also known as Gotu Kola, is a traditional Asian herb used for centuries in Ayurvedic and Chinese medicine. It contains bioactive compounds including triterpenoids and flavonoids that support skin health, cognitive function, and circulation. Modern research supports its use for wound healing, venous insufficiency, and cognitive enhancement.

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Benefits

Enhanced wound healing and collagen synthesis
Improved skin elasticity and reducing cellulite appearance
Venous insufficiency and circulation support
Cognitive enhancement and anxiety reduction
Antioxidant and anti-inflammatory effects
Improved memory and mental clarity

Dosage

Typical Dose

300-600 mg extract daily

Upper Limit

1000 mg daily

Timing

With meals for optimal absorption

Forms & Bioavailability

Standardised extract (30% asiaticoside)

High; standardised extracts provide consistent bioactive compound levels

Dried leaf powder

Moderate; variable compound concentration depending on plant material quality

Fresh plant juice

High; contains active compounds, though less stable than extracts

Side Effects

Mild gastrointestinal upset or nausea
Dizziness or lightheadedness at high doses
Allergic reactions including contact dermatitis in sensitive individuals
Headaches in some users
Potential sedation when combined with other herbs

Interactions

May potentiate sedative effects of benzodiazepines and other CNS depressants
Possible interaction with diabetes medications affecting blood glucose
May enhance blood-thinning effects of anticoagulants like warfarin
Potential interaction with hepatic metabolism via CYP450 enzymes

Research Summary

Centella asiatica has been extensively studied in clinical trials, with evidence supporting its efficacy for venous insufficiency, wound healing acceleration, and cognitive support. Multiple randomised controlled trials demonstrate improvements in skin elasticity, anxiety reduction, and enhanced circulation. However, more rigorous research is needed to establish optimal dosing and long-term safety profiles for specific health conditions.

The Bottom Line on Centella Asiatica

Centella Asiatica is well-researched with strong evidence supporting its primary benefits.It is most commonly used for enhanced wound healing and collagen synthesis and improved skin elasticity and reducing cellulite appearance. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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