Citrulline Malate
performance
Amino acid compound that boosts nitric oxide, blood flow, and exercise endurance.
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Benefits
Dosage
Typical Dose
6-8g pre-workout
Upper Limit
3-10g
Timing
30-60 minutes before training
Forms & Bioavailability
Powder
Standard absorption
Capsule
Standard absorption
Side Effects
Interactions
Research Summary
Strong clinical evidence for improving exercise performance. Multiple RCTs demonstrate increased reps to failure and reduced soreness. 2:1 citrulline:malate ratio most studied.
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The Bottom Line on Citrulline Malate
Citrulline Malate is well-researched with strong evidence supporting its primary benefits.It is most commonly used for enhances nitric oxide production and improves muscular endurance and reps to failure. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Citrulline Malate
See how Citrulline Malate can help with specific health goals: