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Collagen Type III

amino acids

Collagen Type III is a fibrous protein comprising approximately 5-10% of total body collagen, primarily found in skin, blood vessels, and internal organs. It works synergistically with Type I collagen to support structural integrity and elasticity of connective tissues.

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Benefits

Supports skin elasticity and hydration, reducing visible signs of ageing
Strengthens blood vessel walls and promotes cardiovascular health
Enhances gut barrier function and supports intestinal integrity
Improves joint flexibility and supports cartilage health
Promotes hair and nail strength and growth

Dosage

Typical Dose

10-20g daily

Upper Limit

40g daily

Timing

Morning with vitamin C and food for optimal absorption

Forms & Bioavailability

Hydrolysed Collagen Peptides (Type III)

90-95%

Native Collagen Type III

20-30%

Collagen Type III Powder

85-90%

Side Effects

Mild digestive discomfort including bloating or constipation in sensitive individuals
Potential allergic reactions in those with fish or shellfish allergies (marine-sourced collagen)
Unpleasant taste or aftertaste, particularly in unflavoured powders

Interactions

Vitamin C enhances collagen synthesis; concurrent supplementation recommended
May interact with blood-thinning medications; consult healthcare provider if taking anticoagulants
Chelating minerals; separate administration from iron, zinc, and calcium supplements by 2+ hours

Research Summary

Limited human clinical trials exist specifically for Type III collagen supplementation. Most evidence is observational or derived from Type I collagen studies. A 2019 study in Nutrients suggested collagen peptides improved skin elasticity, though results were modest. Type III collagen's role in cardiovascular and gut health is supported by biochemical understanding rather than robust human trials. Further high-quality research is required to establish definitive efficacy and optimal dosing.

The Bottom Line on Collagen Type III

Collagen Type III is well-researched with strong evidence supporting its primary benefits.It is most commonly used for supports skin elasticity and hydration, reducing visible signs of ageing and strengthens blood vessel walls and promotes cardiovascular health. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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