GLA Gamma Linolenic Acid
herbs
GLA (gamma-linolenic acid) is an omega-6 polyunsaturated fatty acid found primarily in plant oils such as borage seed, evening primrose, and black currant seed oils. It is converted in the body to anti-inflammatory compounds that may support joint health, skin condition, and hormonal balance. GLA is distinct from other omega-6 fatty acids due to its potent anti-inflammatory properties.
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Benefits
Dosage
Typical Dose
1.4–2.8g daily
Upper Limit
2.8g daily
Timing
With meals for optimal absorption
Forms & Bioavailability
Borage seed oil softgels
High GLA concentration (20–24%); excellent absorption when taken with fat-containing meals
Evening primrose oil softgels
Moderate GLA concentration (8–10%); requires higher doses for equivalent GLA intake
Black currant seed oil softgels
Moderate GLA concentration (15–17%); good bioavailability
Side Effects
Interactions
Research Summary
Clinical trials demonstrate GLA's efficacy in reducing symptoms of rheumatoid arthritis, with several studies showing improvements in joint pain, swelling, and function. Research supports benefits for atopic dermatitis and other inflammatory skin conditions, though results are mixed for hormonal symptoms. Long-term safety is generally established, though additional research is ongoing regarding optimal dosing and patient-specific efficacy.
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The Bottom Line on GLA Gamma Linolenic Acid
GLA Gamma Linolenic Acid is well-researched with strong evidence supporting its primary benefits.It is most commonly used for joint health and rheumatoid arthritis support and skin condition improvement. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for GLA Gamma Linolenic Acid
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