He Shou Wu

herbs

★★★★★

He Shou Wu, also known as Fo-Ti or Polygonum multiflorum, is a traditional Chinese herb traditionally used to support hair health and longevity. The root contains compounds believed to support circulation and antioxidant activity. Modern research is limited but ongoing regarding its efficacy and safety profile.

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Benefits

✓May support hair pigmentation and reduce premature greying

✓Traditionally used to support cardiovascular health

✓Contains antioxidants that may protect against oxidative stress

✓May support liver function and detoxification

✓Traditionally used to promote longevity and vitality

Dosage

Typical Dose

500-1000 mg daily

Upper Limit

1500 mg daily

Timing

With meals to improve absorption

Forms & Bioavailability

Raw powder

Low to moderate

Processed extract (steamed)

Moderate to high

Capsules

Moderate

Liquid extract

High

Side Effects

⚠Raw or unprocessed forms may cause digestive upset, nausea, and diarrhoea

⚠Potential hepatotoxicity (liver toxicity) reported in some cases, particularly with unprocessed forms

⚠May cause allergic reactions or skin sensitivity in sensitive individuals

Interactions

⚡May interact with anticoagulant and antiplatelet medications due to mild blood-thinning properties

⚡Potential interaction with hepatotoxic medications or substances

⚡May affect iron absorption; separate dosing from iron supplements

Research Summary

Clinical human trials are limited; most evidence is from traditional use and preliminary laboratory studies. Several case reports of hepatotoxicity exist, particularly with raw or improperly processed forms, leading health authorities to recommend processed varieties. Further rigorous research is needed to establish efficacy and optimal safety protocols.

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The Bottom Line on He Shou Wu

He Shou Wu is moderately researched with promising but sometimes mixed evidence.It is most commonly used for may support hair pigmentation and reduce premature greying and traditionally used to support cardiovascular health. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Goal Guides for He Shou Wu

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.