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Holy Basil

adaptogens

Holy Basil (Ocimum sanctum), also known as Tulsi, is an adaptogenic herb traditionally used in Ayurvedic medicine to reduce stress and promote mental clarity. Research suggests it may help regulate cortisol levels and support cognitive function whilst maintaining overall wellness.

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Benefits

Stress and anxiety reduction
Enhanced cognitive function and memory
Improved mood and emotional balance
Antioxidant and anti-inflammatory support
Sleep quality improvement

Dosage

Typical Dose

300-600 mg daily

Upper Limit

1200 mg daily

Timing

Split doses with meals; morning and evening for optimal effect

Forms & Bioavailability

Standardised extract (0.2-2% ursolic acid)

High

Dried leaf powder

Moderate

Herbal tea infusion

Moderate

Liquid extract

High

Side Effects

Rare allergic reactions in sensitive individuals
Potential blood sugar lowering effects at high doses
Minor gastrointestinal upset in some users

Interactions

May potentiate blood pressure and diabetes medications
Possible interaction with anticoagulants at high doses
May enhance sedative effects of benzodiazepines

Research Summary

Clinical studies demonstrate Holy Basil's ability to reduce anxiety and improve stress-related outcomes compared to placebo. Research indicates active compounds like ursolic acid and eugenol contribute to its adaptogenic and neuroprotective properties. Evidence supports its traditional use for cognitive support, though more large-scale human trials are needed to establish optimal dosing and long-term safety profiles.

The Bottom Line on Holy Basil

Holy Basil is well-researched with strong evidence supporting its primary benefits.It is most commonly used for stress and anxiety reduction and enhanced cognitive function and memory. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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