L-Threonine
amino acids
L-Threonine is an essential amino acid that plays a crucial role in protein synthesis, immune function, and collagen formation. It cannot be synthesised by the body and must be obtained through dietary sources or supplementation.
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Benefits
Dosage
Typical Dose
1-3 grams daily
Upper Limit
5 grams daily
Timing
With meals, distributed throughout the day
Forms & Bioavailability
L-Threonine powder
High absorption when taken with food; commonly used in supplementation
L-Threonine capsules
Good bioavailability; convenient dosing format
Free-form L-Threonine
Rapid absorption; immediate availability for utilisation
Side Effects
Interactions
Research Summary
L-Threonine research demonstrates its importance in immune cell production and antibody formation, with studies supporting its role in maintaining mucosal barrier integrity. Evidence suggests supplementation may benefit individuals with inadequate dietary protein intake or those with specific health conditions affecting amino acid metabolism. However, most healthy individuals obtain sufficient threonine through balanced dietary sources.
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The Bottom Line on L-Threonine
L-Threonine is moderately researched with promising but sometimes mixed evidence.It is most commonly used for supports protein synthesis and muscle maintenance and enhances immune system function. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for L-Threonine
See how L-Threonine can help with specific health goals: