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Magnesium

minerals

Essential mineral involved in over 300 enzymatic reactions. Estimated 50-80% of the population is deficient. Critical for sleep, muscle function, and stress management.

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Benefits

Sleep quality improvement
Muscle relaxation and cramp prevention
Stress and anxiety reduction
Blood pressure regulation
Energy production

Dosage

Typical Dose

200-400mg elemental magnesium daily

Upper Limit

800mg daily

Timing

Evening for sleep benefits, split doses for absorption

Forms & Bioavailability

Magnesium Glycinate

High — best for sleep and anxiety, gentle on stomach

Magnesium Threonate

High — crosses blood-brain barrier, best for cognitive function

Magnesium Citrate

Good — may have laxative effect at higher doses

Magnesium Oxide

Low (4%) — cheap but poorly absorbed

Side Effects

Loose stools (especially citrate/oxide forms)
Rare: low blood pressure at very high doses
Generally very safe

Interactions

May reduce absorption of antibiotics (tetracyclines, quinolones)
Can interact with blood pressure medications
Separate from zinc and calcium by 2 hours

Research Summary

Strong evidence for sleep quality, muscle cramps, and blood pressure. Multiple meta-analyses support supplementation for deficiency. Magnesium glycinate is the most studied form for sleep.

The Bottom Line on Magnesium

Magnesium is well-researched with strong evidence supporting its primary benefits.It is most commonly used for sleep quality improvement and muscle relaxation and cramp prevention. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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