Milk Thistle
herbs
Milk thistle is a flowering plant traditionally used to support liver health and detoxification. The active compound silymarin has been studied for its potential hepatoprotective and antioxidant properties.
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Benefits
Dosage
Typical Dose
150-300 mg silymarin daily
Upper Limit
600 mg daily
Timing
with meals for better absorption
Forms & Bioavailability
standardised extract
highest; typically standardised to 70-80% silymarin
capsule
good; convenient dosing
dried herb
lower; variable silymarin content
Side Effects
Interactions
Research Summary
Numerous clinical trials have examined silymarin's effects on liver health, with mixed but generally promising results for liver disease support. Research suggests potential benefits in protecting against liver toxicity and supporting regeneration, though more high-quality studies are needed. Evidence remains strongest for safety and traditional use rather than definitive therapeutic claims.
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The Bottom Line on Milk Thistle
Milk Thistle is moderately researched with promising but sometimes mixed evidence.It is most commonly used for liver support and antioxidant activity. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Milk Thistle
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