Milk Thistle 80% Silymarin
herbs
Milk thistle is a herbal supplement standardised to contain 80% silymarin, the active compound responsible for its hepatoprotective properties. Traditionally used in European medicine for liver support and detoxification, it has been extensively studied for its antioxidant and anti-inflammatory effects.
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Benefits
Dosage
Typical Dose
150-300 mg silymarin daily (equivalent to 200-375 mg of 80% extract)
Upper Limit
600 mg silymarin daily
Timing
With meals to enhance absorption
Forms & Bioavailability
Capsules/Tablets
Moderate; enhanced with standardised extracts and fat-soluble formulations
Liquid Extract
Good; rapid absorption, though taste may be bitter
Standardised Powder
Moderate; consistency varies by formulation
Side Effects
Interactions
Research Summary
Milk thistle has demonstrated hepatoprotective effects in numerous clinical trials, particularly for chemotherapy-induced liver injury and alcoholic liver disease. Silymarin's mechanism involves antioxidant activity, anti-inflammatory effects, and stabilisation of hepatocyte membranes. However, evidence quality varies, and some studies show modest benefit, warranting further rigorous investigation.
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The Bottom Line on Milk Thistle 80% Silymarin
Milk Thistle 80% Silymarin is well-researched with strong evidence supporting its primary benefits.It is most commonly used for liver function support and hepatic detoxification. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Milk Thistle 80% Silymarin
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