Myo-Inositol
vitamins
Myo-inositol is a naturally occurring isomer of inositol, a pseudovitamin involved in cellular signalling and insulin sensitivity. It plays a crucial role in regulating blood glucose metabolism and reproductive health, particularly in women with PCOS. Widely researched for its metabolic and hormonal benefits with a strong safety profile.
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Benefits
Dosage
Typical Dose
2-4 grams daily in divided doses
Upper Limit
4 grams daily
Timing
With meals to enhance absorption; typically split into morning and evening doses
Forms & Bioavailability
Powder
High absorption; excellent solubility in water; allows flexible dosing
Capsules
Good absorption; convenient dosing; may be slower than powder
Tablets
Moderate absorption; consistent dosing; may contain binders affecting absorption
Side Effects
Interactions
Research Summary
Myo-inositol has robust clinical evidence supporting its use in PCOS management, with multiple meta-analyses demonstrating improvements in ovulation rates, metabolic parameters, and hormonal profiles. Studies show efficacy comparable to inositol combined with D-chiro-inositol, though myo-inositol alone remains the most studied form. Research continues into its broader applications in metabolic syndrome and mood disorders.
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The Bottom Line on Myo-Inositol
Myo-Inositol is well-researched with strong evidence supporting its primary benefits.It is most commonly used for improves insulin sensitivity and glucose metabolism and supports ovulatory function in pcos. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.
About Our Research
This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.
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Goal Guides for Myo-Inositol
See how Myo-Inositol can help with specific health goals: