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Neem Leaf

herbs

Neem leaf is a traditional Ayurvedic herb derived from the neem tree (Azadirachta indica) native to India, known for its antimicrobial and anti-inflammatory properties. It has been used for centuries in traditional medicine to support immune function, skin health, and oral hygiene.

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Benefits

Supports immune system function
Promotes healthy skin and may help reduce acne
Supports oral health and gum function
Provides antimicrobial and antifungal properties
May support healthy blood sugar levels

Dosage

Typical Dose

400-600 mg daily

Upper Limit

1200 mg daily

Timing

With meals to improve absorption and reduce gastrointestinal upset

Forms & Bioavailability

Leaf powder

moderate

Capsules

moderate

Dried leaf tea

low

Standardised extract

high

Side Effects

May cause gastrointestinal upset including nausea or diarrhoea in sensitive individuals
Can cause headaches or dizziness at higher doses
May cause allergic reactions in individuals with sensitivity to plants in the Meliaceae family

Interactions

May interact with immunosuppressant medications and reduce their effectiveness
Could potentiate blood sugar-lowering medications, requiring dose adjustments
May have additive effects with anticoagulant medications

Research Summary

Limited clinical research exists on neem leaf in humans, though traditional use and preliminary studies suggest potential antimicrobial and anti-inflammatory effects. Most evidence comes from in vitro and animal studies showing active compounds like azadirachtin possess bioactive properties. More robust human trials are needed to establish efficacy for specific health claims.

The Bottom Line on Neem Leaf

Neem Leaf is moderately researched with promising but sometimes mixed evidence.It is most commonly used for supports immune system function and promotes healthy skin and may help reduce acne. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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