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Quercetin

herbs

Quercetin is a flavonoid antioxidant found naturally in plants, known for its anti-inflammatory and immune-supporting properties. It has been studied for its potential benefits in reducing allergic responses, supporting cardiovascular health, and enhancing athletic performance.

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Benefits

Antioxidant and anti-inflammatory support
Allergy and histamine response management
Cardiovascular health promotion
Athletic performance and endurance
Immune system support

Dosage

Typical Dose

500–1000 mg daily in divided doses

Upper Limit

2000 mg daily

Timing

With meals to enhance absorption; split doses throughout the day

Forms & Bioavailability

Quercetin dihydrate

Standard form with moderate absorption; requires vitamin C or bromelain for enhanced uptake

Quercetin phytosome

Enhanced formulation with improved absorption; bound to phospholipids for better bioavailability

Quercetin glycoside

Plant-derived form with naturally improved absorption compared to standard quercetin

Side Effects

Headaches at high doses
Mild gastrointestinal upset
Flushing or tingling sensations
Kidney irritation with excessive supplementation

Interactions

May enhance effects of immunosuppressants
Potential interaction with certain antibiotics
May potentiate effects of anticoagulants and antiplatelet medications
Can inhibit cytochrome P450 enzymes affecting drug metabolism

Research Summary

Clinical trials demonstrate quercetin's efficacy in reducing allergy symptoms, particularly when combined with vitamin C and bromelain. Studies show promise for cardiovascular benefits including improved endothelial function and blood pressure management. Research on athletic performance suggests modest improvements in aerobic capacity, though results remain inconsistent across studies.

The Bottom Line on Quercetin

Quercetin is well-researched with strong evidence supporting its primary benefits.It is most commonly used for antioxidant and anti-inflammatory support and allergy and histamine response management. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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