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Red Clover

herbs

Red clover (Trifolium pratense) is a legume rich in isoflavones, plant compounds with oestrogenic properties. Traditionally used in herbal medicine, particularly for menopausal symptom relief and bone health support.

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Benefits

May reduce hot flushes and night sweats during menopause
Supports bone mineral density in postmenopausal women
May improve blood circulation and cardiovascular health
Contains antioxidants and anti-inflammatory compounds
Traditionally used to support reproductive health

Dosage

Typical Dose

500-1,500 mg daily of standardised extract (40-80 mg isoflavones)

Upper Limit

2,000-3,000 mg daily

Timing

With meals to enhance absorption and minimise digestive upset

Forms & Bioavailability

Standardised extract (isoflavone-rich)

High (40-80% isoflavone content)

Dried herb/tea

Moderate (variable isoflavone content)

Capsules/tablets

Moderate to high (depends on standardisation)

Side Effects

May cause mild nausea, headache, or gastrointestinal disturbance
Potential allergic reactions in those sensitive to legumes
May cause rash or photosensitivity in some individuals

Interactions

May interact with hormone-sensitive conditions or hormone replacement therapy
Potential interactions with anticoagulants due to vitamin K content
May affect medications metabolised by cytochrome P450 enzymes at high doses

Research Summary

Clinical evidence for menopausal symptom relief is mixed, with some studies showing modest benefits for hot flushes whilst others show minimal effects compared to placebo. Research on bone health shows promise in postmenopausal women, though findings remain inconsistent. Further high-quality trials are needed to establish efficacy and optimal dosing protocols.

The Bottom Line on Red Clover

Red Clover is moderately researched with promising but sometimes mixed evidence.It is most commonly used for may reduce hot flushes and night sweats during menopause and supports bone mineral density in postmenopausal women. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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