Saccharomyces Boulardii

herbs

★★★★★

A probiotic yeast strain derived from Saccharomyces cerevisiae that supports digestive health and immune function by promoting beneficial gut flora and intestinal barrier integrity.

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Benefits

✓Reduces antibiotic-associated diarrhoea and Clostridium difficile infection risk

✓Supports intestinal barrier function and reduces intestinal permeability

✓Enhances immune response through increased IgA production in the gut

✓Alleviates symptoms of traveller's diarrhoea and acute infectious gastroenteritis

✓Promotes beneficial microbial balance and inhibits pathogenic bacteria adhesion

Dosage

Typical Dose

250-500 mg (5-10 billion CFU) daily

Upper Limit

1000 mg (20 billion CFU) daily in divided doses

Timing

With or between meals; separate from antibiotics by 2+ hours

Forms & Bioavailability

Capsule

High (90%+)

Powder

High (90%+)

Sachet

High (90%+)

Side Effects

⚠Mild gastrointestinal disturbance (bloating, constipation) during initial use

⚠Rare fungal infections in severely immunocompromised individuals

Interactions

⚡Significantly reduced efficacy if taken within 2 hours of antibiotics

⚡May interact with antifungal medications (fluconazole, itraconazole)

⚡Caution advised in patients with central venous catheters or severe immunosuppression

Research Summary

Well-established probiotic with robust clinical evidence supporting use in antibiotic-associated diarrhoea (meta-analyses demonstrate 30-40% risk reduction) and traveller's diarrhoea. Safe for most populations; approved by European Commission as a food supplement. Mechanism involves competitive exclusion, antimicrobial peptide production, and intestinal barrier reinforcement.

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The Bottom Line on Saccharomyces Boulardii

Saccharomyces Boulardii is well-researched with strong evidence supporting its primary benefits.It is most commonly used for reduces antibiotic-associated diarrhoea and clostridium difficile infection risk and supports intestinal barrier function and reduces intestinal permeability. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.