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Saffron Extract

herbs

Saffron extract is derived from the stigmas of Crocus sativus and contains active compounds including crocin and safranal. It has been traditionally used in Ayurvedic and Persian medicine, with emerging scientific evidence supporting its use for mood support and cognitive function.

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Benefits

Mood elevation and depression support
Cognitive function and memory
Eye health and vision
Anti-inflammatory properties
Antioxidant activity

Dosage

Typical Dose

15-30 mg daily

Upper Limit

100 mg daily

Timing

With meals to enhance absorption

Forms & Bioavailability

Standardised Extract

High bioavailability; typically standardised to 2-3% crocin for consistent potency

Whole Stigma Powder

Moderate bioavailability; contains full spectrum of compounds but less concentrated

Side Effects

Gastrointestinal upset at high doses
Dizziness or headache
Allergic reactions (rare)
Dry mouth

Interactions

May potentiate effects of SSRIs and serotonergic medications
Possible interaction with anticoagulants
May interact with antiplatelet medications

Research Summary

Clinical trials demonstrate saffron extract's efficacy comparable to some antidepressants for mild-to-moderate depression, with fewer adverse effects. Research supports benefits for cognitive function, particularly in age-related decline and early neurodegenerative conditions. Most evidence comes from Iranian and Asian studies; further large-scale Western clinical trials would strengthen evidence base.

The Bottom Line on Saffron Extract

Saffron Extract is well-researched with strong evidence supporting its primary benefits.It is most commonly used for mood elevation and depression support and cognitive function and memory. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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