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Withania Somnifera Root

adaptogens

Withania Somnifera, commonly known as Ashwagandha, is an adaptogenic herb traditionally used in Ayurvedic medicine to promote stress resilience and overall wellbeing. The root contains bioactive compounds called withanolides that support cortisol regulation and mental clarity. It is widely researched for its anxiolytic and rejuvenating properties.

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Benefits

Stress and anxiety reduction
Improved sleep quality
Enhanced cognitive function
Cortisol regulation
Mood support
Physical endurance and stamina

Dosage

Typical Dose

300-600 mg daily

Upper Limit

1,000-1,200 mg daily

Timing

With meals, preferably morning and evening

Forms & Bioavailability

Root powder

Moderate; enhanced when taken with fat or milk

Standardised extract (withanolides 5-10%)

High; concentrated active compounds for consistent potency

Capsules

Moderate to high; depends on extraction method and standardisation

Side Effects

Drowsiness or sedation at higher doses
Gastrointestinal upset
Headaches in sensitive individuals
Allergic reactions in rare cases

Interactions

Sedatives and sleep aids may have additive effects
Immunosuppressants may be affected due to immune-modulating properties
Hypoglycaemic medications may require monitoring
Thyroid supplements may interact in sensitive individuals

Research Summary

Numerous clinical trials demonstrate Withania Somnifera's efficacy in reducing cortisol levels and anxiety symptoms, with improvements often observed within 4-8 weeks of consistent use. Research supports its neuroprotective properties and potential cognitive benefits, particularly in stress-related cognitive decline. Studies suggest withanolides may support sleep architecture and promote both relaxation and mental resilience.

The Bottom Line on Withania Somnifera Root

Withania Somnifera Root is well-researched with strong evidence supporting its primary benefits.It is most commonly used for stress and anxiety reduction and improved sleep quality. As with any supplement, individual results vary. Start with the lower end of the dosage range and assess for 4-8 weeks before adjusting.

About Our Research

This profile is compiled from peer-reviewed research published on PubMed, the NIH Office of Dietary Supplements, and established nutritional science databases. Dosages reflect clinically-studied amounts from human trials where available. We update profiles as new research emerges. This is not medical advice — consult a healthcare professional before supplementing.

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Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional before starting any supplement, especially if you have existing health conditions or take medication.

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