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Chlorophyll vs Vitamin B12 — Which Should You Take?

Chlorophyll

herbs

Typically £8–£25/month

Vitamin B12

vitamins

Typically £8–£25/month
Feature
Chlorophyll
Vitamin B12
Typical Dosage
100-300mg daily
500-1,000mcg daily
Best Form
Chlorophyllin (water-soluble derivative)
Methylcobalamin
Key Benefits
5 listed
5 listed
Evidence Rating
★★★★★
★★★★
Best Time
With meals for optimal absorption
Morning — may be energising
Upper Limit
1000mg daily
No established upper limit (water-soluble)
Side Effects
3 noted
2 noted

Chlorophyll Benefits

May support wound healing and skin health
Potential antioxidant and anti-inflammatory effects
Could aid natural detoxification processes
May improve body odour reduction
Possible digestive support and gut health benefits

Vitamin B12 Benefits

Energy production
Nerve function and protection
Red blood cell formation
DNA synthesis
May reduce homocysteine levels

Chlorophyll Side Effects

May cause green-coloured stools or urine
Possible mild nausea or constipation in sensitive individuals
Photosensitivity reactions in rare cases

Vitamin B12 Side Effects

Very safe — excess excreted in urine
Rare: acne at very high doses in some individuals

Can You Take Chlorophyll and Vitamin B12 Together?

In most cases, Chlorophyll and Vitamin B12 can be taken together safely. However, always check the interactions section of each supplement and consult a healthcare professional if you take medication or have existing health conditions.

Chlorophyll: May interact with anticoagulant medications due to vitamin K content

Chlorophyll: Could potentially interfere with certain photosensitising medications

Vitamin B12: Metformin reduces B12 absorption — supplement if on metformin

Vitamin B12: Proton pump inhibitors (PPIs) reduce absorption

Which Should You Choose?

Choose Chlorophyll if your primary goal is: may support wound healing and skin health. Choose Vitamin B12 if your primary goal is: energy production.

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Frequently Asked Questions

Is Chlorophyll better than Vitamin B12?

It depends on your goals. Chlorophyll and Vitamin B12 serve different purposes and are often taken together.

Can I take Chlorophyll and Vitamin B12 together?

In most cases, yes. Chlorophyll and Vitamin B12 can be taken together safely. However, always check for specific interactions and consult a healthcare professional if you take medication.

What is the best time to take Chlorophyll?

With meals for optimal absorption

What is the best time to take Vitamin B12?

Morning — may be energising

What are the side effects of Chlorophyll?

May cause green-coloured stools or urine. Possible mild nausea or constipation in sensitive individuals. Photosensitivity reactions in rare cases.

What are the side effects of Vitamin B12?

Very safe — excess excreted in urine. Rare: acne at very high doses in some individuals.

How We Compare Supplements

This comparison is based on published clinical research, peer-reviewed studies from PubMed, and established nutritional science. We evaluate dosages based on clinically-effective amounts, not manufacturer recommendations. Benefits listed have at least moderate evidence from human studies. When evidence is limited or conflicting, we note this.

Disclaimer: This comparison is for educational purposes only and is not medical advice. Always consult a qualified healthcare professional before starting any supplement, especially if you take medication or have existing health conditions.

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