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Folate (B9) vs Magnesium — Which Should You Take?

Folate (B9)

vitamins

Typically £8–£25/month

Magnesium

minerals

Typically £8–£25/month
Feature
Folate (B9)
Magnesium
Typical Dosage
400-800 mcg daily for adults
200-400mg elemental magnesium daily
Best Form
Methylfolate (5-MTHF)
Magnesium Glycinate
Key Benefits
5 listed
5 listed
Evidence Rating
★★★★★
★★★★★
Best Time
With food, preferably at breakfast
Evening for sleep benefits, split doses for absorption
Upper Limit
1,000 mcg daily (upper tolerable intake)
800mg daily
Side Effects
3 noted
3 noted

Folate (B9) Benefits

Supports DNA synthesis and cell division
Reduces homocysteine levels for cardiovascular health
Essential for foetal neural tube development
Enhances mood and supports cognitive function
Supports methylation and detoxification pathways

Magnesium Benefits

Sleep quality improvement
Muscle relaxation and cramp prevention
Stress and anxiety reduction
Blood pressure regulation
Energy production

Folate (B9) Side Effects

Nausea or gastrointestinal upset (typically at high doses)
Headaches or fatigue
Potential B12 deficiency masking with excessive supplementation

Magnesium Side Effects

Loose stools (especially citrate/oxide forms)
Rare: low blood pressure at very high doses
Generally very safe

Can You Take Folate (B9) and Magnesium Together?

In most cases, Folate (B9) and Magnesium can be taken together safely. However, always check the interactions section of each supplement and consult a healthcare professional if you take medication or have existing health conditions.

Folate (B9): Anticonvulsant medications (phenytoin, phenobarbitone) reduce folate absorption

Folate (B9): Methotrexate antagonises folate metabolism

Magnesium: May reduce absorption of antibiotics (tetracyclines, quinolones)

Magnesium: Can interact with blood pressure medications

Which Should You Choose?

Choose Folate (B9) if your primary goal is: supports dna synthesis and cell division. Choose Magnesium if your primary goal is: sleep quality improvement.

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Frequently Asked Questions

Is Folate (B9) better than Magnesium?

It depends on your goals. Folate (B9) and Magnesium serve different purposes and are often taken together.

Can I take Folate (B9) and Magnesium together?

In most cases, yes. Folate (B9) and Magnesium can be taken together safely. However, always check for specific interactions and consult a healthcare professional if you take medication.

What is the best time to take Folate (B9)?

With food, preferably at breakfast

What is the best time to take Magnesium?

Evening for sleep benefits, split doses for absorption

What are the side effects of Folate (B9)?

Nausea or gastrointestinal upset (typically at high doses). Headaches or fatigue. Potential B12 deficiency masking with excessive supplementation.

What are the side effects of Magnesium?

Loose stools (especially citrate/oxide forms). Rare: low blood pressure at very high doses. Generally very safe.

How We Compare Supplements

This comparison is based on published clinical research, peer-reviewed studies from PubMed, and established nutritional science. We evaluate dosages based on clinically-effective amounts, not manufacturer recommendations. Benefits listed have at least moderate evidence from human studies. When evidence is limited or conflicting, we note this.

Disclaimer: This comparison is for educational purposes only and is not medical advice. Always consult a qualified healthcare professional before starting any supplement, especially if you take medication or have existing health conditions.

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